A novel solution for the time-dependent probability of gene fixation or loss under natural selection.
نویسندگان
چکیده
Kimura proposed a solution for the time-dependent probability of fixation, or loss, of a gene under selection. Example calculations suggest the formulas are prone to numerical inaccuracies. An alternative solution is proposed; the correctness of the solution is confirmed by numerically solving the Kolmogorov backward equation and by simulation.
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ورودعنوان ژورنال:
- Genetics
دوره 168 2 شماره
صفحات -
تاریخ انتشار 2004